The Evidence

Built on real-world implementation,
not theory.

We have already built the foundation. Every critical component of VLOOP has been executed in the field — across the United States and Ghana.

We Have Already Built the Foundation

Two proving grounds, one workflow

United States

VLOOP Community Pilot

  • 5 community cardiovascular evaluation events
  • Older adult population with portable echocardiography
  • AI-enabled workflow with successful cardiology referrals

Lessons learned

Community demand exists. Workflow is feasible. Detection alone is not enough — navigation is essential.

Ghana — HeartLINK

Community Cardiovascular Network

0+

Patients evaluated

0+

Echocardiograms

0+

Patients referred

This proposal is built on real-world implementation, not theory.

Scientific Foundation

Two landmark studies opened the door

HUDDLE and PREVUE-VALVE each answered a critical question — and each left one unanswered.

HUDDLEPeer-Reviewed

Prevalence of Cardiovascular Disease and Risk Factors Among Former National Football League Players

Okoh AK, et al. J Am Coll Cardiol. 2024;83(19).

What HUDDLE demonstrated

  • Community cardiovascular evaluation is feasible
  • Portable echocardiography successfully identifies structural heart disease
  • Older adults actively engage with community-based programs

HUDDLE answered: Can we identify disease? Yes.

One critical question remained: What happens after identification?

PREVUE-VALVEPeer-Reviewed

Population Prevalence of Valvular Heart Disease in the United States: The PREVUE-VALVE Study

Brener MI, et al. J Am Coll Cardiol. 2026;87(23).

What PREVUE demonstrated

  • Structural valve disease is far more common than recognized
  • Prevalence increases substantially with age
  • Significant numbers of older adults remain completely undiagnosed

PREVUE answered: How common is disease? More common than expected.

One critical question remained: How do we consistently connect these patients to specialty care?

The Missing Link

VLOOP completes the pathway

HUDDLE and PREVUE established that disease exists and can be found. VLOOP is the implementation bridge between diagnosis and treatment — the critical infrastructure that neither study was designed to build.

HUDDLE

Can we find disease?

PREVUE

How common is it?

VLOOP

Can we identify, triage and connect patients?

Valve Clinic

Treatment and follow-up